Posts Tagged ‘brain imaging’

National Geographic Explorer’s “Science of Evil” Considers Situational & Neurological Factors in Stories of Research, Wartime Abuses & a Serial Killer’s Baptism

Monday, June 3rd, 2013

Our last post was about an episode of the documentary series National Geographic Explorer called “Born to Rage,” which focused on a topic very germane to ponerology, namely “the Warrior Gene,” a genetic variant that predisposes many men to aggression and violence.

Little did I know that, in the course of researching for that post, I would come across an episode of Explorer seemingly even more precisely relevant to ponerology than that. But that is just what happened.

Ponerology is defined as “the science of evil.” And, to my surprise, I came across a 2008 episode of Explorer actually entitled “Science of Evil.”

Just as in “Born to Rage,” the main framework for this episode’s exploration is established by the narrator early on. This time the guiding quote is this:

“Evil. It is blamed for cruelty beyond our mind’s comprehension. Is it a dark force outside of us that we are all vulnerable to, that we must work to resist? Is it inside of us, a stain on the soul, a dysfunction of the brain? Or just a word used to distance ourselves from inherently human behavior?” (more…)

New Study Evokes Debate Over the Ethics of Using Biological Markers to Predict, Preempt Harmful Activity

Friday, March 29th, 2013

One of the “holy grails” of ponerology – and an achievement that will inevitably force us to confront extremely challenging ethical dilemmas – is an improved ability to predict harmful behavior before it happens.

Dr. Kent Kiehl of the Mind Research Network has been one of the more active researchers investigating what we can learn from brain imaging of psychopaths. And he and colleagues have recently published, in the Proceedings of the National Academy of Sciences of the United States of America, a study entitled “Neuroprediction of future rearrest.”

The study involved having 96 soon-to-be-released male prisoners perform computer tasks that required quick decision-making and inhibition of impulsive responses, while their brains were observed using functional magnetic resonance imaging (fMRI). The researchers focused in on the brain region known as the anterior cingulate cortex (ACC) and found that, when controlling for other known risk factors, those prisoners with less ACC activity than their fellow study participants were about twice as likely to be rearrested within 4 years of release as those with higher ACC activity.

We’ve already mentioned, in previous stories, that reduced cingulate cortex function is associated with psychopathy and has been identified in some violent criminal offenders.

The question is, as we zero in on markers like this – whether they be certain anatomical or functional characteristics of the brain, particular genetic features or anything else – what is the most ethical way in which to use this knowledge? (more…)

Neuroscientist James Fallon’s Work & Life Shed Light on How Psychopathic Killers are Made…and Perhaps Prevented

Tuesday, March 5th, 2013

One of the most challenging and important questions in ponerology is whether conditions associated with reduced empathy and conscience, and thus with increased likelihood of harmful malicious and neglectful activity, are caused by nature (genes, biology, etc.) or nurture (environment, upbringing, etc.)

Most who work in the fields that study aspects of this question take the view that the answer involves some combination of the two.

But this still leaves us with another question. In what proportion do each of these factors contribute in which people?

One remarkable case offers some fascinating insight on the subject.

Dr. James Fallon

James Fallon, Ph.D. is a highly decorated neuroscientist and Professor Emeritus of Anatomy and Neurobiology at University of California, Irvine. Dr. Fallon has several areas of expertise. One is adult stem cells. Another is psychiatry. Specifically, he is interested in the relationships between brain imaging (he has served as Director of UC Irvine’s Human Brain Imaging Center), genetics and various psychiatric conditions, including schizophrenia, depression and addictions.

An Extraordinary Experiment

Aware of his specialties, for many years, Fallon’s colleagues have sent him brain images they wished to have him analyze.

At one point this interchange took the form of an experiment.

Colleagues sent him 70 MRI scans of brains belonging to people ranging from healthy to mentally ill. Included in the batch were scans of brains belonging to killers, including some notorious ones. But Fallon had no idea which scanned brain belonged to whom.

Nonetheless, he was able to identify differences in five of the scans so dramatic that he could recognize them as the markers of psychopathy. And it turned out that he was correct. The five scans on which he zeroed in actually were those from the brains of psychopathic serial killers. (more…)